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ｔ(9;2 2 ) (ｑ34 ;ｑ1 1 )易位可见于 95 %以上慢性粒细胞白血病 (ＣＭＬ)和 2 0 %～ 2 5 %急性淋巴细胞白血病 (ＡＬＬ) ,该易位使 9号染色体上的ａｂｌ基因和 2 2号染色体上的ｂｃｒ基因重排形成ｂｃｒ/ａｂｌ融合基因 ,导致正常ａｂｌ基因编码的Ｐ1 4 5蛋白变为Ｐ2 1 0蛋白
The translocation of t (9; 2 2) (q34; q1 1) is found in more than 95% of chronic myeloid leukemia (CML) and 20% ~ 25% of acute lymphoblastic leukemia (ALL) On the abl gene and on chromosome 2 bcr gene rearrangement to form bcr / abl fusion gene, resulting in normal abl gene encoding P1 4 5 protein into P2 10 protein