日本神奈川县稻叶等对13名(男5,女8)白塞氏病患者,投予 OP—1206(前列腺素 E_1制剂)15μg/日,分三次口服,同时并用甲巯丙脯酸50～75mg/日,分2～3次口服,经过半年的治疗,观察其各种症状及化验值的变化。其结果对口腔阿夫他溃疡和结节性红斑,具有显著的疗效。与用安慰剂的灯照组(12例)、单用 OP—1206组(22例)相比,口腔阿夫他溃疡约从第8周,结节性红斑约从第12周开始,每月 Thirteen (5 males and 8 females) patients with Behcet’s disease were inoculated orally with OP-1206 (Prostaglandin E-1 preparation) 15 μg / day orally in three times and were treated with captopril 50-100 mg once daily for 5 days. 75mg / day, 2 to 3 times orally, after six months of treatment, observe its various symptoms and laboratory changes in value. The results of oral alfatar and erythema nodosum, with significant effect. Compared with the placebo lamp group (12 cases), OP-1206 alone group (22 cases), oral alfuter ulcer from about the first 8 weeks, nodular erythema from about the 12th week, every month