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目的分析乳腺浸润性导管癌的钼靶X线征象,探讨其BI-RADS分级与雌激素受体(ER)、孕激素受体(PR)及人表皮生长因子受体(HER-2)表达的相关性。方法回顾性分析手术后病理证实的94例乳腺浸润性导管癌患者的钼靶X影像及病理资料,根据钼靶X线分级结果进行分组,分析BI-RADS分级与ER、PR、HER-2表达的相关性。结果(1)ER在乳腺浸润性导管癌BI-RADS分级中阳性高表达率有显著性差异。(2)乳腺浸润性导管癌中ER、PR、HER-2的阳性高表率在4级最低,在3级最高。结论乳腺浸润性导管癌中ER、PR、HER-2阳性表达与BI-RADS分级有一定的相关性。
OBJECTIVE: To analyze the mammographic X-ray findings of invasive ductal carcinoma of the breast and to investigate the relationship between BI-RADS grade and expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor (HER-2) Correlation. Methods The mammographic X-ray images and pathological data of 94 patients with invasive ductal carcinoma of the breast confirmed by pathology were retrospectively analyzed. The grade of BI-RADS and the expression of ER, PR and HER-2 Relevance. Results (1) The positive expression rate of ER in BI-RADS grading of invasive ductal carcinoma was significantly different. (2) The positive rates of ER, PR and HER-2 in breast invasive ductal carcinoma were the lowest in grade 4 and the highest in grade 3. Conclusion The positive expressions of ER, PR and HER-2 in invasive ductal carcinoma of breast are related to the grade of BI-RADS.