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患者,男性,60岁,因无痛性头部肿瘤于1979年10月住院。血清中存在M成分(IgA型),肿瘤活检系浆细胞瘤,骨髓浆细胞数14%,诊断为多发性骨髓瘤。采用环磷酰胺及强的松龙治疗。1980年5月血清M成分和肿瘤消失。停药后5个月再发,转用马法兰、强的松治疗无效。体检前额至头顶部见6个肿瘤,右胸锁关节部触及2×2cm无痛性硬瘤。轻度贫血,
The patient, male, 60 years old, was hospitalized in October 1979 for painless head tumors. M component (IgA type) was present in the serum, and plasma tumors were biopsy in the tumor. The number of bone marrow plasma cells was 14%, and the diagnosis was multiple myeloma. Cyclophosphamide and prednisolone treatment. In May 1980, serum M components and tumors disappeared. After 5 months of stopping the drug, it was reinstated and the treatment with Maflan and prednisone was ineffective. Six tumors were seen at the top of the forehead and the right chest lock joints touched a 2×2cm painless hard tumor. Mild anemia,