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蛋白糖基化一度被认为只存在于真核生物中,但近年越来越多的研究显示,无论是N-连接糖基化还是O-连接糖基化都同样存在于原核微生物中,其中就包括一些病原菌。糖蛋白的存在对这些病原菌的生命过程至关重要,研究者希望通过对病原菌糖蛋白的研究,探索出新的方式来预防及治疗由相关病原菌引发的疾病。该文对一些重要病原菌内糖蛋白的研究进展进行了综述。
Protein glycosylation was once thought to exist only in eukaryotes, but more and more studies in recent years showed that both N-linked glycosylation and O-linked glycosylation are also present in prokaryotic microorganisms, among which Including some pathogens. The existence of glycoprotein is crucial to the life process of these pathogens. Researchers hope to explore new ways to prevent and treat the diseases caused by related pathogens through the research on the glycoprotein of pathogen. This article reviews the progress of glycoproteins in some important pathogens.