中线恶性肉芽肿是耳鼻咽喉科的险恶疾病。临床表现为上呼吸道中线部位炎症、溃疡进行性组织坏死，最终侵犯重要器官，引起大出血或因衰竭而死亡。本病在病理上往往只能见到急、慢性炎症、肉芽组织坏死现象，多数找不到恶性肿瘤细胞，因其病情凶险，以往本病常命名为恶性肉芽肿 Midline malignant granuloma is a sinister disease of the otolaryngology. Clinical manifestations of the upper respiratory tract inflammation of the midline, ulcer tissue necrosis, the final violation of vital organs, causing bleeding or due to failure and death. The disease often only see the pathology of acute and chronic inflammation, granulation tissue necrosis, the majority can not find malignant cells, because of its dangerous condition, in the past the disease often named malignant granuloma