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本文比较51名健康人,51名慢性胃病患者和41名消化道癌症患者尿蝶呤水平,结果胃癌、贲门癌、结肠癌、食管癌患者的尿蝶呤含量明显高于健康人及浅表性胃炎患者,差异非常显著(P<0.01),并发现某些被认为与癌前状态有关的慢性胃病(包括肠上皮化生、上皮细胞不典型增生、残胃炎及萎缩性胃炎等)患者尿蝶呤水平也大幅度增高,与癌症患者相近而与浅表性胃炎有显著差异。
This study compared the levels of urine pterin in 51 healthy people, 51 patients with chronic gastritis and 41 patients with digestive tract cancer. The results showed that the levels of uropterin in patients with gastric cancer, cardiac cancer, colon cancer, and esophageal cancer were significantly higher than those in healthy people and superficial ones. In patients with gastritis, the difference was very significant (P<0.01), and some patients with chronic gastropathy (including intestinal metaplasia, dysplasia of epithelial cells, residual gastritis and atrophic gastritis) believed to be related to precancerous conditions were found. The level of guanine is also significantly higher, similar to cancer patients and significantly different from superficial gastritis.