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所有的胶原性疾病皆能累及肾脏,但程度不同。全身性系统性红斑性狼疮(SLE)累及肾脏最重。本文重点讨论SLE对肾脏损伤,其它用后面表格说明。目前将SLE引起的肾炎,依其组织学所见分为局灶性增殖性肾炎,弥漫性增殖性肾炎及膜性肾炎三种。各型之间可以移行。最近注意到局灶性肾炎可转变为其它两型,另外两型之间几乎不能移行。 SLE性肾炎用萤光抗体法检查,肾小球可见有抗原—抗体复合物沉着。SLE时在血中有多种抗体。并发肾炎的频率为46～75％,以此为初发症状者为3～6％。并发肾炎多在初期(一年以内者占35％),病程达5年并发肾脏损伤者比较少见(15％以下)。
All collagen diseases can affect the kidneys, but to different degrees. Systemic systemic lupus erythematosus (SLE) involves the kidneys heaviest. This article focuses on SLE injury to the kidney, the rest of the table with the instructions. Nephritis is currently caused by SLE, according to the histological findings divided into focal proliferative glomerulonephritis, diffuse proliferative glomerulonephritis and membranous nephritis three. You can move between various types. Recently noted that focal nephritis can be transformed into the other two types, the other two almost can not migrate. SLE glomerulonephritis with fluorescent antibody test, glomerular antigen-antibody complexes can be seen calm. SLE in the blood when there are a variety of antibodies. The frequency of nephritis is 46 ~ 75%, as the initial symptoms were 3 to 6%. Nephritis and more in the early stage (35% within one year), duration of 5 years of renal damage associated with relatively rare (15%).