新生儿呼吸窘迫综合症（NRDS）是早产　儿常见的并发症,病死率极高,近年来,使用　机械通气收到一定疗效,但仍欠满意,国内虽　有使用表面活性物质（PS）治疗NRDS的尝　试,但经验尚不多,现将我院对7例重症　NRDS使用PS报告如下: 临床资料 　 一、一般资料 　 1998年12月～2000年11月在本院出生　并收入NICU的7例确诊为重症NRDS的患　儿中,男6例,女1例,胎龄30±17周,体重1500±300g。7例均有明显三凹征（100％）, 呻吟样呼吸3例（57.1％）,面色发钳6例 Neonatal respiratory distress syndrome (NRDS) is a common complication of premature infants, the mortality rate is extremely high. In recent years, the use of mechanical ventilation received a certain effect, but still not satisfied with the use of surfactant (PS) although the domestic treatment of NRDS Of the experience, but experience is not much, now our hospital on the seven cases of severe NRDS using PS reported as follows: Clinical data First, the general information December 1998 ~ November 2000 in our hospital and income NICU diagnosed as Severe NRDS in children, 6 males and 1 females, gestational age 30 ± 17 weeks, weight 1500 ± 300g. All 7 cases had obvious concave sign (100%), groaning breathing in 3 cases (57.1%), facial hair clamp in 6 cases