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目的研究古钩藤水煎液的镇痛抗炎药理作用。方法采用小鼠热板法和扭体法镇痛实验,观察古钩藤水煎液的镇痛作用,观察对小鼠毛细血管通透性和二甲苯对小鼠耳廓肿胀的影响,观察其抗炎作用。结果古钩藤水煎液能显著提高小鼠痛阈值,降低毛细血管通透性,抑制由二甲苯所致的炎症反应,可显著减轻小鼠耳廓肿胀。结论古钩藤水煎剂有明显的镇痛和抗炎作用。
Objective To study the analgesic and anti-inflammatory pharmacological effects of ancient decoction decoction. Methods Analgesic experiments with mouse hot plate method and writhing method were used to observe the analgesic effect of ancient decoction decoction, observe the effect of capillary permeability of mice and the effect of xylene on ear swelling of mice. Anti-inflammatory effect. Results The decoction of ancient rhynchophylla can significantly increase the pain threshold, reduce the capillary permeability, inhibit the inflammatory reaction caused by xylene, and significantly reduce the ear swelling in mice. Conclusion The ancient decoction decoction has obvious analgesic and anti-inflammatory effects.