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目的了解皮革企业周围暴露于二甲基甲酰胺(DMF)老年人群的健康状况,为制定防制措施提供依据。方法整理分析DMF暴露地区和非暴露地区老年人群体格检查、血常规、肝肾功能指标等体检资料,数据采用epidata3.02录入、SPSS 19.0统计分析。结果 2组对象白细胞、空腹血糖、舒张压、低密度脂蛋白、谷丙转氨酶、谷草转氨酶差异无统计学意义(P>0.05);暴露组血红蛋白、血小板、收缩压、甘油三脂、总胆红素和血尿素氮高于对照组,差异均有统计学意义(P<0.01);暴露组总胆固醇、高密度脂蛋白和血清肌酐低于对照组,差异均有统计学意义(P<0.01)。结论DMF暴露对老年人群中的血液、心脏、肝脏和肾脏可能有一定的影响,距离皮革企业越近影响越大,应积极加强对DMF暴露环境的监测和老年人群的防护。
Objective To understand the health status of elderly people exposed to dimethylformamide (DMF) in the leather industry and provide a basis for the development of control measures. Methods Physical examination data, such as physical examination, blood routine, liver and kidney function indexes of elderly population in DMF exposure area and non-exposure area were analyzed and analyzed. The data were recorded by epidata 3.02 and SPSS 19.0 statistical analysis. Results There was no significant difference in leukocyte, fasting blood glucose, diastolic blood pressure, low density lipoprotein, alanine aminotransferase and aspartate aminotransferase in the two groups (P> 0.05). The hemoglobin, platelet, systolic blood pressure, triglyceride, (P <0.01). The levels of total cholesterol, high density lipoprotein and serum creatinine in the exposed group were lower than those in the control group (P <0.01), and the differences were statistically significant . Conclusion DMF exposure may affect the blood, heart, liver and kidneys in the elderly population to some extent. The closer the distance to the leather business, the greater the monitoring of exposure to DMF and the protection of the elderly.