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目的 :确定细菌性阴道病 (BV)在妊娠妇女中的发病情况及对母婴的不良影响。方法 :以四项临床诊断指标中符合 3项并阴道涂片革兰染色细菌评分≥ 7分作为BV的诊断标准 ,对 40 6名初次产检的孕妇进行BV的筛查 ,追踪其中 34名单纯合并BV者和 2 5 2名无BV者的妊娠结局。结果 :1 妊娠期BV的发病率为 11 82 % ,其在中孕早期的患病率为9 72 % ,孕晚期患病率为 14 2 8%。 2 有BV组的早产、组织学绒毛膜羊膜炎和新生儿高胆红素血症发生率分别为 14 71%、8 82 %和 5 5 88% ,高于无BV组 ,分别为 3 17%、0 79%和 34 13 % ,P =0 .0 0 7、P =0 .0 13、P =0 .0 2 3。结论 :BV是妊娠妇女最常见的阴道感染性疾病之一 ,其与早产、组织学绒毛膜羊膜炎和新生儿高胆红素血症等不良妊娠结局有关 ,有必要对孕妇进行BV的筛查和治疗。
Objective: To determine the incidence of bacterial vaginosis (BV) in pregnant women and the adverse effects on mothers and babies. Methods: According to the diagnostic criteria of BV, the three clinical diagnostic indexes which meet the criteria of vaginal smear Gram stain of bacteria ≥ 7 were used to screen BV, and the screening of 40 6 pregnant women with initial check-up was followed up with 34 simple mergers BV and 252 non-BV pregnancy outcomes. Results: 1 The incidence of BV in pregnancy was 11 82%, which was 9 72% in early pregnancy and 14 2 8% in late pregnancy. The incidence of histological chorioamnionitis and neonatal hyperbilirubinemia in BV group was 14 71%, 82 82% and 55 88% respectively, which were higher than those in the non-BV group, which were respectively 3 17% , 0 79% and 34 13%, P = 0.07, P = 0.013, P = 0.023. CONCLUSIONS: BV is one of the most common vaginal infections in pregnant women and is associated with adverse pregnancy outcomes such as preterm birth, histologic chorioamnionitis, and neonatal hyperbilirubinaemia. It is necessary to screen BV for pregnant women And treatment.