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【目的】观察持续泵注多巴胺防治剖宫产蛛网膜下腔阻滞后低血压的效果和安全性。【方法】选择本院 ASAⅠ~Ⅱ级的单胎足月行剖宫产术的产妇60例，随机分为对照组和多巴胺组，在蛛网膜下腔穿刺成功注药后，多巴胺组以5~8μg/(kg·min)的速率持续经静脉泵入多巴胺，对照组则泵入生理盐水。监测和记录麻醉前、麻醉后3 min、5 min、10 min、15 min、20 min、25 min 时产妇的收缩压(SBP)、舒张压(DBP)、心率(HR)、呼吸频率(RR)、血氧饱和度(SpO 2)，观察比较低血压及恶心呕吐等不良反应发生情况。新生儿娩出后1 min 和5 min 行 Apgar 评分，并抽取脐动脉血进行血气分析。【结果】与麻醉前的基础值相比较，对照组产妇麻醉后的各时间点均出现血压下降(P <0.05)。多巴胺组产妇麻醉后各个时段的血压均高于对照组(P <0.05)，低血压和术中恶心呕吐的发生率显著低于对照组，且两组相比较差异有显著性(P0.05)。【结论】小剂量持续输注多巴胺可有效防治剖宫产术蛛网膜下腔阻滞后的低血压。“,”Objective]To explore the efficacy and safety of continuous infusion of dopamine in the preven-tion of hypotension after spinal anesthesia during cesarean section.[Methods]A total of 60 ASAⅠ~Ⅱ,aged 24~35 years,women with single fetus were randomly divided into control and dopamine groups.After suc-cessful subarachnoid puncture and drug injection,an intravenous infusion of dopamine was continuously ad-ministered at 5~8 μg/(kg·min)in dopamine group while the same dosage of normal saline in control group. The values of systolic pressure (SBP),diastolic blood pressure (DBP),heart rate (HR),respiratory rate (R) and oxygen saturation (SPO 2 )were recorded at pre-anesthesia and 3,5,10,1 5,20 and 25 min post-anesthe-sia.Such adverse reactions as hypotension,nausea and vomiting were observed.Neonatal Apgar scores and pH value of umbilical artery blood were recorded.[Results]Compared with T0 values,maternal blood pressures were significantly lower in control group after anesthesia(P <0.05).Blood pressures were remarkably higher in dopamine group than those in control group (P <0.05 ).And the incidences of hypotension,nausea and vomiting were significantly lower than those of control group (P < 0.05 ).No statistical inter-group differ-ences existed in neonate umbilical arterial pH,1 min Apgar score or 5 min Apgar score.[Conclusion]A con-tinuous infusion of low-dose dopamine is both safe and effective for preventing hypotension after subarachnoid block during cesarean section.