论文部分内容阅读
我校军队卫生学教研室和药学院药剂学教研室研制的复方氨基酸(肝氨要素)冲剂是一种新型治疗肝病的氨基酸制剂。该制剂是根据肝功能不全时代谢的特点,以高支低芳氨基酸混合物、多种维生素和微量元素等为原料研制而成。经模拟肝纤维化和急性肝衰动物实验表明,该制剂能防止急性肝损伤引起的血清转氨酶活性的明显升高;提高血清总蛋白、白蛋白含量,以及血清支链氨基酸与芳香族氨基酸克分子的比值;纠正血清氨基酸谱紊乱;减轻肝组织变性、坏死和纤维增生程度,并能预防肝昏迷和改善肝昏迷症状及体征。
The Compound Amino Acid (Hepatic Ammonia Factor) granules developed by the Military Health Teaching and Research Section of our school and the Pharmaceutical Research Office of the School of Pharmacy are a novel amino acid preparation for the treatment of liver diseases. The preparation is based on the characteristics of metabolism in liver dysfunction, high-low-aromatic amino acid mixture, a variety of vitamins and trace elements as raw materials developed. Experimental animal experiments simulating hepatic fibrosis and acute hepatic failure have shown that the preparation can prevent the elevation of serum transaminase activity caused by acute liver injury; increase serum total protein, albumin, and serum branched-chain amino acid and aromatic amino acid molecule The ratio; to correct the serum amino acid spectrum disorders; reduce liver degeneration, necrosis and fibrosis, and can prevent hepatic coma and improve hepatic coma symptoms and signs.