炎症是具有血管系统的活体组织对损伤因子所发生的复杂的防御反应。炎症可以改变癌基因和抑制癌基因(包括蛋白质编码基因和非编码小分子RNA基因)的表达和转化,以促进细胞向恶性转变。肺癌是一种严重威胁人类健康与生命的恶性肿瘤,而炎性反应是导致肺癌发生的重要因素。现就炎性反应在肺癌发生中的促进作用综述国内外的研究进展。 Inflammation is a complex defensive response to damaging factors by living tissue with a vasculature. Inflammation can change oncogenes and suppress the expression and transformation of oncogenes (including protein-coding genes and non-coding small RNA molecules) to promote the malignant transformation of cells. Lung cancer is a malignant tumor that seriously threatens human health and life, and inflammatory response is an important factor that causes lung cancer. Now on the role of inflammatory response in the development of lung cancer reviewed the progress of research at home and abroad.