论文部分内容阅读
对1965～1995年1747例年龄<41岁的霍奇金淋巴瘤(HL)幸存者心血管疾病(CVD)发生率进行评估,用多因素Cox回归和竞争风险分析法对CVD的治疗效果进行定量分析。在平均随访18.7年后,心肌梗死(MI)和充血性心力衰竭(CHF)的发生率比普通患者显著增加[标准化发病比率(SIRS)分别为3.6和4.9],每年每万病人的MI和CHF分别增加35.7例和25.6例。所有CVD的SIRS持续增加至少25
The incidence of cardiovascular disease (CVD) in 1747 Hodgkin lymphoma (HL) survivors aged <41 years from 1965 to 1995 was assessed and the effect of CVD was quantified using multivariate Cox regression and competition risk analysis analysis. After a mean follow-up of 18.7 years, the incidence of myocardial infarction (MI) and congestive heart failure (CHF) was significantly higher than that of normal patients (standardized incidence rates (SIRS) 3.6 and 4.9, respectively) Respectively, an increase of 35.7 cases and 25.6 cases. SIRS for all CVDs continues to increase by at least 25%