1958年自从Powell等发现第一个β-阻滞剂——双氢异丙基肾上腺素以来,β-阻滞剂应用于临床已有15年以上,业已证实该类药物在许多临床疾病中有效。萘羟心安(Corgard,学名nadolol)是美国施贵宝药厂发现和研制的新一代非选择性β-阻滞剂,主要适用于高血压和心绞痛的临床治疗。 Since the discovery of the first β-blocker, dihydro-iPA, by Powell et al. In 1958, β-blockers have been clinically used for more than 15 years and have been shown to be effective in many clinical conditions . Cornell (Corgard, nadolol) is a new generation of non-selective β-blocker discovered and developed by Squibb, which is mainly used in the clinical treatment of hypertension and angina pectoris.