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Objective:To study the effects of Aidi Dripping Pills on immune functions of the tumor-bearing mouse on the basis of the previous experimental studies on its tumor-inhibiting and life-prolonging effects.Methods:By using the transplantation tumor mouse models,the effects of Aidi Dripping Pills on the lymphocyte transformation rate and the hemolysin formation in the S180 tumor-bearing mice,and on the phagocytic function of macrophages in the abdominal cavity of H22 tumor-bearing mice were investigated.Results:In the 2.25 g/kg and 1.125 g/kg Aidi Dripping Pills groups,the lymphocyte transformation rates in the S180 tumor-bearing mice were significantly higher than that of the control group(P<0.01).In all the Aidi Dripping Pills groups,HC50 significantly increased(P<0.01 or P<0.05),carbon granular clearance significantly raised,and both the phagocytic index and phagocytic coefficient were significantly higher than those in the control group(P<0.01 or P<0.05).Conclusion:The Aidi Dripping Pills can significantly increase the cellular immune function,the humoral immune function and the phagocytic function of the mononuclear-macrophages,so it may show anti-tumor effects by enhancing the function of the reticuloendothelial system.
Objective: To study the effects of Aidi Dripping Pills on immune functions of the tumor-bearing mouse on the basis of the previous experimental studies on its tumor-inhibiting and life-prolonging effects. Methods: By using the transplantation tumor mouse models, the effects of Aidi Dripping Pills on the lymphocyte transformation rate and the hemolysin formation in the S180 tumor-bearing mice, and on the phagocytic function of macrophages in the abdominal cavity of H22 tumor-bearing mice were investigated. Results: In the 2.25 g / kg and 1.125 g / kg Aidi Dripping Pills groups, the lymphocyte transformation rates in the S180 tumor-bearing mice were significantly higher than that of the control group (P <0.01) .In all the Aidi Dripping Pills groups, HC50 significantly increased or P <0.05), carbon granular clearance significantly raised, and both the phagocytic index and phagocytic coefficient were significantly higher than those in the control group (P <0.01 or P <0.05) .Conclusion: The Aidi Dripping Pi lls can significantly increase the cellular immune function, the humoral immune function and the phagocytic function of the mononuclear-macrophages, so it may show anti-tumor effects by enhancing the function of the reticuloendothelial system.