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星形细胞瘤是神经上皮源性肿瘤中最常见的一类肿瘤。占颅内肿瘤的17%,占神经上皮源性肿瘤的40%,肿瘤向周围“蟹足样”浸润性生长,且无包膜形成。磁共振波谱(magnetic resonance spectroscopy,MRS)是随着磁共振成像(magnetic resonance imaging,MRI)发展起来的唯一的一种无创性研究活体组织的代谢情况和生化指标的技术,目前已在中枢神经系统疾病的临床工作和科学研究中得到广泛应用。它能活体检测脑组织,提供关于神经元功能、细胞能量代谢、细胞膜增殖和崩解以及选择性神经递质活动等信息,为脑肿瘤的临床治疗和科学研究提供了一条新的途径。磁共振波谱在星形细胞瘤的肿瘤实质区及肿瘤周围区的代谢物比值有助于肿瘤分级诊断,并且MRS有助于判定肿瘤的浸润边界,指导临床术中立体定位及组织病理学检查。此外,代谢-解剖叠加伪彩图体现的肿瘤本身的异质性在高低级别肿瘤中也有差异。近年来,许多学者研究发现磁共振波谱在星形细胞瘤患者有无癫痫发作者的代谢物水平不同,二者间的相关研究需要进一步深入。
Astrocytomas are the most common type of tumor in neuroepithelial tumors. Accounting for 17% of intracranial tumors, accounting for 40% of neuroepithelial tumors, the tumor to the surrounding “crab foot” infiltration of growth, and no envelope formation. Magnetic resonance spectroscopy (MRS) is the only noninvasive technique to study the metabolic status and biochemical indexes of living tissue developed along with magnetic resonance imaging (MRI). At present, it has been used in the central nervous system Disease clinical work and scientific research has been widely used. It can detect brain tissue in vivo and provide information on neuronal function, cellular energy metabolism, cell membrane proliferation and disintegration, and selective neurotransmitter activity, providing a new approach for the clinical treatment and scientific research of brain tumors. Magnetic resonance spectroscopy in the astrocytoma of the tumor parenchyma and tumor area surrounding the ratio of metabolites contribute to tumor grade diagnosis, and MRS help determine the tumor infiltration boundary, to guide the clinical intraoperative stereotaxic and histopathological examination. In addition, the heterogeneity of the tumor itself reflected by the metabolic-anatomical overlay pseudo-color map also varies among high and low grade tumors. In recent years, many scholars study found that magnetic resonance spectroscopy in astrocytoma patients with or without epilepsy metabolites at different levels, the correlation between the two needs further study.