研究表明 ,对目前使用的乙型肝炎疫苗出现低应答或无应答者可能具有某种遗传素质 ,因此 ,在一些特定人群中似乎需要较强免疫原性的疫苗。最近 ,Smith Kline Beecham公司研制出新佐剂系统 SBAS4,其主要成分为铝剂与 3- 0脱酰单磷酰脂质 A,它通过贮存点形成、激活巨噬细胞和向 T? Studies have shown that people who have low or no response to currently used Hepatitis B vaccines may have some genetic predisposition and thus appear to require stronger immunogenic vaccines in selected populations. Recently, Smith Kline Beecham Company developed a new adjuvant system, SBAS4, consisting mainly of an aluminum agent and 3- deacylated monophosphoryl lipid A, which forms through the site of storage, activates macrophages,