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目的 探讨肝病患者红细胞平均体积 (MCV)、红细胞体积分布宽度 (RDW )、血小板的 4项指数变化与病情的关系。方法 应用Coulter公司JT—IR全自动血液计数仪检测 181例肝病患者和 10 0例健康者为对照组。结果 ( 1)肝硬化组、慢乙肝组、急性肝炎组MCV、RDW、MPV均显著高于对照组 (P <0 .0 1) ,PLT、PDW、PCT均显著低于对照组 (P <0 .0 1) ;( 2 )MCV、RDW、MPV之间成正相关关系 ,PLT、PDW、PCT之间亦成正相关关系 ,MCV、RDW、MPV与PLT、PDW、PCT之间成负相关关系。结论 ( 1)MCV、RDW可以反映肝病病情的轻重和肝功能损害程度 ;( 2 )血小板 4项参数测定为肝病患者血小板功能的初步评价提供了简便、快速、可靠的方法
Objective To investigate the relationship between the changes of MCV, RDW and platelet indices in patients with liver disease. Methods 181 cases of liver disease and 100 healthy controls were detected by Coulter JT-IR automatic blood counter as control group. Results (1) MCV, RDW and MPV in cirrhosis group, chronic hepatitis B group and acute hepatitis group were significantly higher than those in control group (P <0.01), PLT, PDW and PCT were significantly lower than those in control group There was a positive correlation between MCV, RDW and MPV, and a positive correlation between PLT, PDW and PCT. There was a negative correlation between MCV, RDW, MPV and PLT, PDW and PCT. Conclusion (1) MCV and RDW can reflect the severity of liver disease and the extent of liver damage. (2) The determination of platelet parameters provides a simple, rapid and reliable method for the preliminary evaluation of platelet function in patients with liver disease