原发全面性癫痫患者脑内无器质性病变,常规影像学检查不能发现异常。目前普遍认为丘脑皮层网络在原发全面性癫痫的发病中起着重要作用。多模态神经影像学可从结构、功能、血流及代谢等方面观察大脑异常,为研究原发全面性癫痫的发病机制提供方法。本文对原发全面性癫痫的丘脑皮层网络的神经影像学研究进展进行综述。 Primary comprehensive epilepsy patients with no organic brain lesions, routine imaging examination can not be found abnormalities. It is generally accepted that thalamic cortex network plays an important role in the pathogenesis of primary generalized epilepsy. Multimodality neuroimaging can be used to observe brain abnormalities from the aspects of structure, function, blood flow and metabolism, and to provide a method for studying the pathogenesis of primary generalized epilepsy. This review summarizes the neuroimaging studies of thalamic cortical networks of primary generalized epilepsy.