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近年来研究表明,端粒重复序列结合蛋白在调节端粒的长度和功能方面起着十分重要的作用。这种作用依赖或不依赖于端粒酶,与细胞衰老和肿瘤发生、发展有密切关系。本文介绍近年来发现的一些重要的端粒重复序列结合蛋白研究进展。
Recent studies have shown that telomeric repeat binding proteins play a very important role in the regulation of telomere length and function. This effect depends on or not dependent on telomerase, and cellular aging and tumor development, are closely related. This article describes some important telomere repeat binding proteins discovered in recent years.