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目的探索前列腺癌发病的危险因素和保护因素,为预防前列腺癌发病提供依据。方法采用1:1匹配的病例对照研究方法,用专门设计的调查表对我科148例前列腺癌病例及148例非肿瘤患者进行1对1的询问调查,采用条件logistic回归分析法对所获得的调查资料进行统计学分析。结果单因素分析显示:高龄、肥胖、睾酮水平高、有前列腺炎和有输精管术结扎术史是前列腺癌的危险因素,首次遗精时间晚及首次性生活时间晚是前列腺癌的保护因素。多因素分析显示:高龄、肥胖及有前列腺炎是前列腺癌的危险因素,首次遗精时间晚及首次性生活时间晚是前列腺癌的保护因素。结论前列腺癌的发病是多因素共同参与的结果 。
Objective To explore the risk factors and protective factors in the pathogenesis of prostate cancer and provide evidence for preventing the onset of prostate cancer. Methods A 1: 1 matching case-control study was used to investigate the relationship between 148 cases of prostate cancer and 148 cases of non-tumor patients in our department. One-on-one questionnaires were surveyed using conditional logistic regression analysis. Survey data for statistical analysis. Results Univariate analysis showed that the elderly, obesity, high level of testosterone, prostatitis and vasectomy were the risk factors of prostate cancer. The time of first spermatorrhea and the first sex life were the protective factors of prostate cancer. Multivariate analysis showed that advanced age, obesity and prostatitis were the risk factors of prostate cancer. The time of first spermatorrhea and the first sex life were the protective factors of prostate cancer. Conclusion The incidence of prostate cancer is a result of many factors involved.