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为探讨免疫分型及细胞遗传学在急性白血病（AL）中的诊断价值，对30例FAB标准难以分类的AL患者进行了检查。结果显示FAB难以分型的AL可以分成三组：（1）M2／M3难以鉴别，主要根据t（8；21）、t（15；17）等染色体异常诊断；（2）过氧化物酶（POX）阴性的AL，主要根据免疫分型诊断。主要包括M0、M7、部分M1、M5等急性髓细胞白血病及急性淋巴细胞白血病；（3）杂合型急性白血病，免疫分型是最重要的诊断手段。结果提示免疫分型及染色体分析是形态学诊断的重要补充，应成为AL的常规诊断手段。
In order to investigate the diagnostic value of immunophenotyping and cytogenetics in acute leukemia (AL), 30 AL patients that were difficult to classify by FAB criteria were examined. The results showed that the ALBs with difficult FAB classification can be divided into three groups: (1) M2/M3 is difficult to distinguish, mainly based on chromosomal abnormalities such as t(8;21), t(15;17); (2) Peroxidase ( POX)-negative AL is diagnosed mainly by immunophenotyping. Mainly include M0, M7, some M1, M5 and other acute myeloid leukemia and acute lymphoblastic leukemia; (3) heterozygous acute leukemia, immunophenotyping is the most important diagnostic tool. The results suggest that immunophenotyping and chromosome analysis are important supplements for morphological diagnosis and should be a routine diagnostic tool for AL.