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局部毒性对皮肤及皮下组织可能有广泛的损伤。化学和物理因素如酸、碱、烈性溶媒、热、冷、电磁能和超声波均可伤害皮肤。微生物如真菌、细菌、螺旋体、病毒能侵入皮肤并影响其正常功能。接触某些有毒的化学物质能引起严重的全身中毒。这些毒品与水化、温暖和浸渍的部位密切接触,能使局部和全身遭受更严重的损伤。本文仅选择其中一些主要部份作一简要介绍。
Local toxicity may have extensive damage to the skin and subcutaneous tissue. Chemical and physical factors such as acids, alkalis, potent solvents, heat, cold, electromagnetic energy and ultrasound can damage the skin. Microorganisms such as fungi, bacteria, spirochetes, viruses can invade the skin and affect their normal function. Contact with certain toxic chemicals can cause serious systemic poisoning. These drugs are in close contact with hydrated, warm and impregnated parts, which can result in even more severe localized and systemic injuries. This article only chooses some of the main part for a brief introduction.