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为探讨动脉灌注大剂量抗癌药对胃粘膜的影响，作者对７３例病人在灌注抗癌药前后行胃镜及胃粘膜病理检查，结果动脉化疗组消化道反应比静脉化疗组明显降低，统计学处理具有非常显著意义（Ｐ＜０．０１）。而化疗前后的镜下胃粘膜改变及病理组织学检查结果均无统计学意义（Ｐ＞０．０５）。动脉灌注化疗对中晚期恶性肿瘤患者无疑是一种安全有效的治疗方法，只要操作得当及预防治疗得力，即可防止或减少胃肠粘膜损害的发生。
To investigate the effect of arterial infusion of high-dose anticancer drugs on gastric mucosa, the authors performed gastroscopy and pathological examinations of gastric mucosa before and after infusion of anticancer drugs in 73 patients. As a result, the gastrointestinal reaction in the arterial chemotherapy group was significantly lower than that in the intravenous chemotherapy group. Treatment was very significant (P < 0.01). There were no statistically significant changes in the gastric mucosal changes and histopathological examination before and after chemotherapy (P>0.05). Arterial infusion chemotherapy is undoubtedly a safe and effective treatment for patients with metaphase and advanced malignant tumors. As long as they are properly handled and prevented, they can prevent or reduce the occurrence of gastrointestinal mucosal lesions.