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目的观察阿昔洛韦治疗小儿手足口病的临床疗效观察。方法选取我院2011年5月至2012年6月将手足口病患者48例,随机分为观察组和对照组各24例,观察组采用口服阿昔洛韦5～10mg(kg·d),对照组采用病毒唑片5～10mg(kg·d),观察临床体疗效。结果观察组的症状体征消失比对照组早,观察组总有效率91.7%,对照组总有效率79.2%,两组比较差异有统计学意义(P<0.05)。结论阿昔洛韦治疗手足口病疗效好,副作用小,值得临床推广。
Objective To observe the clinical efficacy of acyclovir in the treatment of hand-foot-mouth disease in children. Methods Forty-eight patients with hand-foot-mouth disease were selected from May 2011 to June 2012 in our hospital and randomly divided into observation group (24 cases) and control group (24 cases). The acyclovir 5 to 10 mg (kg · d) The control group was treated with Ribavirin 5 ~ 10mg (kg · d) to observe the clinical curative effect. Results The symptoms and signs of the observation group disappeared earlier than the control group. The total effective rate was 91.7% in the observation group and 79.2% in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion acyclovir treatment of hand-foot-mouth disease with good side effects, worthy of clinical promotion.