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目的 :探究七氟醚全麻喉罩通气在小儿眼科肿瘤检查中的应用效果。方法:选取2015年9月至2016年2月上海复旦大学附属儿科医院眼科收治的86例眼科肿瘤患儿,将所有患儿随机分为试验组与对照组,其中试验组43例患儿给予七氟醚全麻喉罩通气检查,对照组43例患儿给予静脉氯胺酮检查,比较两组患儿在手术前,诱导时、诱导5 min后、手术结束心率、呼吸频率以及二氧化碳分压情况。比较两组患儿诱导时间以及苏醒时间,并观察两组患儿不良反应的发生情况。结果:试验组患儿在手术过程中心率[(137.9±24.1)次·min~(-1) vs(167.5±34.9)次·min~(-1),P<0.05]及麻醉结束时心率[(139.2±29.8)次·min~(-1) vs(153.4±27.4)次·min~(-1),P<0.05]明显低于对照组。患儿呼吸频率和二氧化碳分压方面,麻醉前、诱导时、诱导后5min以及麻醉结束时都没有明显的区别(P>0.05)。且试验组患儿进行诱导的时间[(2.6±0.8)min vs(6.5±1.5)min,P<0.05]以及苏醒的时间明显短于对照组[(3.6±0.8)min vs(32.6±5.2)min,P<0.01],试验组不良反应的发生率也低于对照组(11.6%vs 23.3%,P<0.05)。结论:对眼肿瘤患儿进行检查时,选用七氟醚全麻喉罩通气与传统的氯胺酮麻醉相比可以减少检查对患儿心率、呼吸频率以及二氧化碳分压造成的影响。
Objective: To investigate the application effect of sevoflurane anesthesia laryngeal mask ventilation in pediatric eye tumor examination. Methods: From September 2015 to February 2016, 86 cases of ophthalmic tumors admitted to the Pediatric Hospital of Fudan University in Shanghai were enrolled. All children were randomly divided into experimental group and control group, of which 43 cases in experimental group were given seven In the control group, 43 children were given intravenous ketamine for examination, and the heart rate, respiratory rate and carbon dioxide partial pressure at the end of surgery were compared between the two groups before and after induction. The induction time and recovery time of the two groups were compared, and the occurrence of adverse reactions in both groups were observed. Results: The heart rate of the experimental group during the operation [(137.9 ± 24.1) min -1 (167.5 ± 34.9) min -1, P 0.05] and the heart rate at the end of anesthesia (139.2 ± 29.8) min -1 (153.4 ± 27.4) min -1, P <0.05] was significantly lower than that of the control group. Respiratory rate and carbon dioxide partial pressure in children, pre-anesthesia, induction, 5min after induction and anesthesia at the end of no significant difference (P> 0.05). (2.6 ± 0.8) min vs (6.5 ± 1.5) min, P <0.05], and the time of recovery in the experimental group was significantly shorter than that in the control group [(3.6 ± 0.8) min vs (32.6 ± 5.2) min, P <0.01]. The incidence of adverse reactions in the experimental group was also lower than that in the control group (11.6% vs 23.3%, P <0.05). CONCLUSIONS: In seizures of children with ocular tumors, the use of sevoflurane anesthesia for ventilation in the laryngeal mask compared with conventional ketamine anesthesia can reduce the impact of examination on heart rate, respiratory rate, and carbon dioxide partial pressure in children.