婴儿肥厚性幽门狭窄 (IHPS)是婴儿幽门肥厚导致的幽门出口梗阻 ,常于出生后 3～ 5周内发生 ,可引起脱水、体重下降 ,电解质紊乱等 ,但致死者罕见。虽然IHPS病因未明 ,但既往报道表明 ,与IHPS应用红霉素有关。本文评价新生儿过早应用红霉素与肥厚性幽门狭窄的联系。1985～ 1997? Hypertrophic pyloric stenosis (IHPS) is a pyloric outlet obstruction caused by pyloric hypertrophy in infants. It often occurs within 3 to 5 weeks after birth and can cause dehydration, weight loss, electrolyte imbalance, etc., but deaths are rare. Although the etiology of IHPS is unknown, previous reports indicate that erythromycin is associated with IHPS. This article evaluates the neonatal premature use of erythromycin and hypertrophic pyloric stenosis. 1985 ~ 1997?