作者将53名健康婴幼儿分为两组,其中29名在3、5和7月龄时接种b型流感杆菌(Hib)荚膜多糖(PRP)与DTP混合菌苗,并在18月龄时单独接种PRP。另外24名在3、5和7月龄时接种PRP与白喉类毒素结合菌苗(PRP-D)(同时亦接种DTP),其中半数在14月龄时再接种PRP-D,另外一半则在18月龄时接种。结果表明,3月龄婴儿接种后烦躁发生率PRP+DTP组为52%,PRP-D组为58%。局部反应(注射部位微红)发生率,PRP+DTP The authors divided 53 healthy infants into two groups, 29 of whom were inoculated with a mixed vaccine of Hib capsular polysaccharide (PRP) and DTP at 3, 5, and 7 months of age, and at 18 months of age PRP alone. Another 24 were vaccinated with PRP and diphtheria toxoid-conjugated vaccine (PRP-D) (also inoculated with DTP) at 3, 5 and 7 months of age, with half of those vaccinated PRP-D at 14 months of age and the other at Vaccination at 18 months of age. The results showed that the rate of irritability in 3-month-old infants was 52% in the PRP + DTP group and 58% in the PRP-D group. Local reaction (injection site reddish) incidence, PRP + DTP