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应用免疫组化染色技术检测 p16及 PCNA基因在膀胱移行细胞癌中的表达，旨在探讨两者与膀胱移行细胞癌分级及预后的关系。 1材料与方法 1． 1材料 收集我院 1978～ 1992年间，手术切除膀胱移行细胞癌 55例。其中男性 44例，女性 11例，年龄 28～ 77岁，中位年龄 58.87岁。随访时
Immunohistochemical staining was used to detect the expression of p16 and PCNA in transitional cell carcinoma of the urinary bladder. The aim was to investigate the relationship between the expression of p16 and PCNA in grading and prognosis of bladder transitional cell carcinoma. 1 Materials and methods 1. 1 Materials collected in our hospital from 1978 to 1992, surgical resection of bladder transitional cell carcinoma in 55 cases. There were 44 males and 11 females, aged 28-77 years, with a median age of 58.87 years. At follow-up