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选择未治疗过的口腔、口咽、喉及下咽鳞癌患者165例,其中85例为中子治疗,80例为光子治疗,两组年龄、肿瘤部位和TN分期相似。治疗量:中子总吸收量15.6～16.7Gy,光子为54～56Gy,全程四周以上20次完成治疗。随访期最短5年,最长8年。结果:两组局部病灶长期控制率无显著差异,中子治疗组为44%(37/85),光子组为45%(36/80);中子治疗组于治疗区发生软组织肉瘤,光子组无复发;中子、光子治疗组5年生存率分别为24%(20/85)和34%(27/80),10年生存率分别为14%和30%,局部无瘤5年生存率分别为
Among 165 untreated patients with oral, oropharyngeal, laryngeal and hypopharyngeal squamous cell carcinomas, 85 were treated with neutrons and 80 were treated with photons. The age, tumor site, and TN stage were similar in the two groups. Therapeutic volume: The total neutron absorption is 15.6 ~ 16.7Gy, the photon is 54 ~ 56Gy, complete treatment for more than 20 times throughout the entire process. The shortest follow-up period is 5 years and up to 8 years. Results: There was no significant difference in the long-term control rate between the two groups, 44% (37/85) in the neutron treatment group and 45% (36/80) in the photon group; soft tissue sarcoma occurred in the treatment group in the neutron treatment group, photon group No recurrence; 5-year survival rates in neutron and photon therapy groups were 24% (20/85) and 34% (27/80), 10-year survival rates were 14% and 30%, respectively, and local 5-year survival rates without tumors. Respectively