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目的:观察国产雷贝拉唑对幽门螺杆菌根除和溃疡愈合的疗效。方法:75例消化性溃疡患者,随机分为观察组28例服用雷贝拉唑、克拉霉素及呋喃唑酮;对照1组24例用奥美拉唑替代雷贝拉唑,其余与观察组相同;对照2组23例用泮托拉唑替代雷贝拉唑,其余与观察组相同。用药结束后2 8d复查。结果:各组总有效率和幽门螺杆菌清除率比较无统计学差异(P>0．05)。结论:国产雷贝拉唑三联短程疗法治疗溃疡病疗效确切。
Objective: To observe the curative effect of domestic rabeprazole on Helicobacter pylori eradication and ulcer healing. Methods: Seventy-five patients with peptic ulcer were randomly divided into observation group (n = 28) taking rabeprazole, clarithromycin and furazolidone. In control group 1, 24 patients were treated with omeprazole instead of rabeprazole, and the rest were the same as the observation group. 23 cases of control group 2 with pantoprazole instead of rabeprazole, the rest with the same observation group. 28d after the end of medication review. Results: There was no significant difference in total effective rate and Helicobacter pylori clearance between each group (P> 0.05). Conclusion: Domestic rabeprazole triple short-term therapy for the treatment of ulcer disease is effective.