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目的对抗高血压联合用药进行成本-效果分析。方法以3组高血压联合药物方案:A组(氨氯地平5 mg,早晨服),B组(福辛普利10 mg,早晨服),C组(非洛地平5 mg,早晨服),采用药物学手段进行分析评价。结果 3组药物治疗高血压的总有效率分别为96.0%、84.0%、88.0%,经比较,差异无统计学意义(P>0.05);C组成本最低,有较好的成本-效果比。结论非洛地平为临床较合理的抗高血压药物。
Objective To analyze the cost-effectiveness of antihypertensive combination therapy. Methods A total of three groups of patients with hypertension were enrolled: group A (amlodipine 5 mg, morning service), group B (fosinopril 10 mg, morning service), group C (felodipine 5 mg, morning service) Pharmacological means for analysis and evaluation. Results The total effective rates of the three groups of drugs for the treatment of hypertension were 96.0%, 84.0% and 88.0% respectively. There was no significant difference between the two groups (P> 0.05). The lowest cost of the C group was the better cost-effect ratio. Conclusion Felodipine is a more reasonable antihypertensive drug in clinic.