1临床资料患者男,37岁。30年前无明显诱因于右颊部出现米粒大小红色小丘疹,逐渐增多、增大,发展至鼻部、双颊、下颌部和背部,中线部位最为明显,无任何自觉症状,未治疗。患者既往体健,无遗传性疾病史及药敏史。系统检查未见异常。神志清楚,反应敏捷,智力正常。皮肤科情况:鼻部、双颊、下颌部可见密集淡红色柔软的丘疹,直径约1~10mm,大部分已经融合成 1 Clinical data Patient male, 37 years old. 30 years ago, there was no obvious incentive to appear on the right cheek rice-sized red papules, gradually increased, increased to the nose, cheeks, jaw and back, the most obvious midline, without any symptoms, untreated. Past history of patients with no history of genetic disease and susceptibility history. No abnormal system check. Conscious, responsive, mental normal. Dermatology: the nose, cheeks, jaws visible dense soft red papules, the diameter of about 1 ~ 10mm, most of them have been integrated into