多毛细胞白血病(又称白血性网状内皮细胞增生症)占白血病的2～5%,发病率约为0.2～0.5/10万。Bouroncle 等于1958年首先报告26例,认为是一种独立的疾病,病人的血液中有一种网状细胞或组织细胞。Schrek 等于1966年发现细胞边缘有大量绒毛,因此把它们称为毛细胞。Plenderleith 于1970年开始把本病命名为多毛细胞白血病(hairy cell leukemia,HCL)。本文就近年来国内外文献对 HCL 之诊断和治疗作一介绍。诊 Hairy cell leukemia (also known as white blood reticuloendotheliosis) accounts for 2 to 5% of leukemia, the incidence of about 0.2 to 0.5 / 100,000. Bouroncle was equal to the first report of 26 cases in 1958, considered as an independent disease, the patient’s blood has a reticular cells or tissue cells. Schrek was equal to 1966 found a large number of cells at the edge of the hair, so they are called hair cells. Plenderleith began the disease in 1970 named hairy cell leukemia (HCL). This article in recent years, domestic and foreign literature on the diagnosis and treatment of HCL make an introduction. Clinic