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肝炎和胆道闭锁是新生儿高结合胆红素血症的最常见原因。胆总管囊肿是一种较少见的胆道异常,新生儿患者可伴有胆道闭锁。上述3种疾病凭常规实验室检查不易鉴别。胆道闭锁者若早期作肝肠造瘘术极为有效;不满60天的新生儿作此手术,胆汁持续引流者可达91%,手术年龄超过3月者仅17%,故早期诊断极为重要。作者自1982年2月至1983年4月用超声和核素闪烁显象研究了15例持续性高胆红素血症的新生儿,男10例,女5例,年龄7天～2岁。在肝胆闪烁显象检查之前给苯巴比妥5mg/kg/d,分两次口服,连续至少5天。静脉注射~(99m)锝-DISIDA,以后间隔一定时间从正面及侧面观察其显象,并注意示踪剂是否进入胃肠道。15例直接血胆红素3.7～15.7ml/dl,血清总胆红
Hepatitis and biliary atresia are the most common causes of hyperbilirubinemia in newborns. Common bile duct cyst is a rare biliary abnormalities, neonatal patients may be associated with biliary atresia. The above three diseases are not easy to identify with routine laboratory tests. If biliary atresia for early hepatic enterostomy surgery is extremely effective; less than 60 days of newborns for this operation, continued drainage of bile up to 91%, surgical age over only 17% of March, so early diagnosis is extremely important. From February 1982 to April 1983, 15 patients with persistent hyperbilirubinemia, 10 males and 5 females, aged 7 days to 2 years, were studied by sonography and nuclide scintigraphy. Phenobarbital 5mg / kg / d before hepatobiliary flicker imaging examination, orally twice in a row for at least 5 days. Intravenous ~ (99m) technetium-DISIDA, after a certain period of time from the front and side of the observed imaging, and pay attention to whether the tracer into the gastrointestinal tract. 15 cases of direct bilirubin 3.7 ~ 15.7ml / dl, serum total bile red