DIC is not a clinical entity in itself. Instead, it al-ways occurs secondary to a broad spectrum of variousdiseases. DIC may be defined as an acquired syndromecharacterized by the activation of intravascular coagula-tion up to intravascular fibrin formation. Although thetrigger for the activation of the coagulation system mayvary depending on the underlying condition, it is usually DIC is not a clinical entity in itself. Instead, it al-ways occurs secondary to a broad spectrum of various diseases. DIC may be defined as an acquired syndrome characterized by the activation of intravascular coagula- tion up to intravascular fibrin formation. Although the trigger for the activation of the coagulation system mayvary depending on the underlying condition, it is usually