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作者检测了近绝经年龄尚未经绝和绝经1～10年以上健康妇女169例的血浆中促性腺激素(FSH、LH)和卵巢分泌激素(E_2、E_1、P、T);空腹血钙、磷及碱性磷酸酶;桡骨远、中段1/3交界处的骨盐量。检测结果:完全绝经前FSH、LH开始升高,E_2、E_1、P、T开始下降;绝经后FSH、LH进一步升高,E_2、E_1、P、T迅速下降,且骨吸收大于骨形成,导致骨盐丧失。绝经头3年失骨较快,每年平均丧失2.2％,绝经3～4年后,促性腺激素和卵巢分泌激素相对稳定,失骨减慢,每年平均丧失0.73％。
The authors tested the plasma levels of gonadotropin (FSH, LH) and ovarian hormones (E_2, E_1, P, T) in 169 healthy women who had not yet had menopause and who had not yet had menopause for more than 1 to 10 years. Their fasting blood calcium and phosphorus And alkaline phosphatase; radial distance, the middle of the 1/3 junction bone mineral content. The results showed that FSH and LH began to increase and E_2, E_1, P and T began to decline before the complete menopause. FSH and LH increased further after menopause. E_2, E_1, P and T decreased rapidly and bone resorption was greater than bone formation, Loss of bone salt. During the first 3 years of menopause, the bone is rapidly lost, with an average loss of 2.2% per year. After 3 to 4 years of menopause, the secretion of gonadotropins and ovaries is relatively stable and the bone loss slows down with an average loss of 0.73% per year.