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观察HFRSⅠ、Ⅱ型灭活疫苗人体接种后的抗体持续性。方法：采用IFAT、MCPENT法检测荧光抗体及中和抗体。结果：大洼县用上海产沙鼠苗（Ⅰ型）加强免疫后回年，中和抗体阳性率为323％，荧光抗体阳性率为774％；葫芦岛市用地鼠苗（Ⅱ型）加强免疫后1年，中和抗体及荧光抗体阳性率分别为5.14％、77.1％。结论：两型疫苗免疫后抗体均有较好的保护性和持续性。
Observe the persistence of antibodies after human inoculation of HFRSⅠ and Ⅱ inactivated vaccines. Methods: Fluorescent and neutralizing antibodies were detected by IFAT and MCPENT. Results: The positive rate of neutralizing antibody was 323% and the positive rate of fluorescent antibody was 774%. The positive rate of neutralizing antibody was up to 774% in Hawajiao Miao (type I) After 1 year, the positive rates of neutralizing antibody and fluorescent antibody were 5.14% and 77.1% respectively. Conclusion: The two types of vaccines after immunization antibodies have good protection and continuity.