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目前国内在预防婴儿营养性佝偻病的实际工作中,对维生素 D 用量的意见颇不一致,有人主张400国际单位(u)/日即足,认为剂量过大不但造成浪费,且可引起维生素 D 中毒。但也有人认为每月10万 u(3333u/日)长期服用仍不能完全防止佝偻病发生,主张继续加大剂量。为此在北京市佝偻病协作组支持下,我院对所管辖的6个居委会所有1978年出生的小儿,进行维生素糖丸预防佝偻病效果的观察(糖丸由黑龙江佝偻病协作组专为北京协作组科研配糊,每丸含Vit D_25万 u),除个别儿童未能坚持服药或自行加用其他 Vit D 制剂外,余61例资料较完整,现分析如下:
At present, the opinions on the dosage of vitamin D are rather inconsistent in the actual work of preventing nutritional rickets in infants. Some advocate that 400 IU / day is sufficient, which means that the dosage is too large, not only causing waste, but also causing vitamin D poisoning. However, some people think that a long-term administration of 100,000 inhabitants per day (3333u / day) still can not completely prevent the occurrence of rickets, advocating continuing to increase the dosage. To this end with the support of the Beijing Association of rickets, our hospital on the jurisdiction of the six neighborhood committees all children born in 1978, the observation of the effect of vitamin sugar pills to prevent rickets (sugar pills by the Heilongjiang rickety team for the Beijing Cooperation Group research With paste, each pill containing Vit D2500 u), in addition to individual children failed to adhere to medication or self-use with other Vit D preparations, more than 61 cases more complete information, are analyzed as follows: