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目的 探讨甲状腺腺瘤术后内分泌治疗的必要性。方法 对 10 0例次手术后甲状腺腺瘤标本用SP法测定TSH受体 ,瘤体周围的甲状腺组织连续病理切片检查有无存在微小瘤灶 ,并按随机抽签法将病人分成A ,B两组 ,A组口服甲状腺片治疗 ,B组不用任何治疗。术后定期测定血T3,T4 ,TSH浓度 ,131I扫描及B超检查残存甲状腺。结果 甲状腺腺瘤10 0 %存在TSH受体 ,8%有微小瘤灶。A组病人血T3,T4 ,TSH及残存甲状腺正常 ;B组病人血T3,T4 下降 45例 (90 % ) ,TSH升高 41例 (82 % ) ,残存甲状腺增生、肿大 48例 (96 % ) ,出现甲状腺结节或肿块 33例 (6 6 % )。结论 甲状腺腺瘤术后由于甲状腺功能不足及腺瘤具有多灶性特点 ,需要口服甲状腺素 ,以防止高TSH血症 ,预防肿瘤复发
Objective To discuss the necessity of endocrine therapy after thyroid adenoma surgery. Methods 100 cases of thyroid adenoma after surgery were measured by SP method TSH receptor. Thyroid tissue around the tumor was examined by continuous pathological examination for the presence of small tumor, and the patients were divided into A and B groups according to random drawing. Group A was treated with oral thyroid tablets. Group B did not need any treatment. Blood T3, T4, TSH concentrations, 131I scans, and B-ultrasound residual thyroid were measured periodically after surgery. RESULTS: TSH receptors were present in 10% of thyroid adenomas, and 8% were small foci. Blood group T3, T4, TSH, and residual thyroid glands were normal in group A; 45 cases (90%) of blood T3 and T4 were decreased in group B; 41 cases (82%) were elevated in TSH; 48 cases of residual thyroid hyperplasia and enlargement (96%) ) There were 33 cases (66%) of thyroid nodules or lumps. Conclusion After thyroid adenoma due to thyroid dysfunction and adenoma with multifocal characteristics, oral thyroxine is needed to prevent hyperthyroidism and prevent tumor recurrence.