椭偏光学生物传感器是用来探测和研究特定生物分子及生物分子间相互作用的技术。其基本原理是利用椭偏成像技术实时显示吸附在固体表面上的多元生物分子吸附层的厚度分布和生物分子相互作用所引起的膜层的微小厚度变化。在一个固体表面上制备多种对待测生物分子具有亲和性的生物分子吸附层,当该表面浸入溶有待测的特定生物分子的溶液,其亲和性会使这种生物分子主动与表面上相应生物分子（和抗体对抗原的亲和性）相互作用,并结合成复合生物分子,使表面上该处 Ellipsometry biosensors are techniques used to probe and study the interactions between specific biomolecules and biomolecules. Its basic principle is the use of ellipsometry imaging technology real-time display of adsorption on the solid surface of the multi-biomolecular adsorption layer thickness distribution and biomolecular interactions caused by the film thickness of the small changes. On a solid surface, a variety of biomolecule adsorbed layers having affinity for the biomolecule to be tested are prepared. When the surface is immersed in a solution of a specific biomolecule dissolved in the solution to be tested, its affinity makes the biomolecule actively interacting with the surface The corresponding biomolecules (and the affinity of the antibody for the antigen) interact and bind to the complex biomolecule such that the surface of the biomolecule