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对一例牙源性透明细胞癌的研究结果显示,透明性肿瘤细胞可见线粒体明显增生、肿胀,此为本病例光镜下透明细胞产生的原因。在肿胀的线粒内可见糖原及脂滴沉积,脂滴尚见于不少透明细胞胞浆内。作者推测本病例肿瘤细胞线粒体增生明显、线粒体内糖原沉积的特征可能与其侵袭力强、复发、转移早等生物学行为有关。作者尚提出牙源性透明细胞癌的发病年龄可能与预后有关。
The results of a case of odontogenic clear cell carcinoma showed that the clear tumor cells showed obvious proliferation and swelling of mitochondria, which is the reason for the clear cells under the light microscope in this case. Visible in the swollen mitochondria glycogen and lipid droplets deposition, lipid droplets are still seen in many transparent cytoplasm. The authors speculate that the tumor cells mitochondria proliferation in this case, mitochondrial glycogen deposition may be characterized by its invasion, recurrence, early metastasis and other biological behavior. The authors suggest that the age of onset of odontogenic clear cell carcinoma may be related to the prognosis.