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目的 :评价赖氨匹林加甲氧氯普胺治疗偏头痛的疗效与安全性。方法 :偏头痛病人 10 4例分成 2组 :治疗组 52例 ,男性 15例 ,女性 37例 ,年龄35a±s 12a ;对照组 52例 ,男性 13例 ,女性 39例 ,年龄 37a± 11a。头痛发作时 ,病人随机交替口服内含赖氨匹林 0 .9g加甲氧氯普胺 10mg的胶囊(治疗组 )或内含淀粉的胶囊 (对照组 ) 1粒。结果 :治疗组服药 4h总有效率为 88% ;对照组总有效率为 2 9%。 2组总有效率比较差别有非常显著意义(P <0 .0 1) ,未见严重不良反应。结论 :赖氨匹林加甲氧氯普胺治疗偏头痛安全、可靠。
Objective: To evaluate the efficacy and safety of meticillin plus metoclopramide in the treatment of migraine. Methods: A total of 104 patients with migraine were divided into two groups: treatment group, 52 cases, male 15, female 37, age 35a ± s 12a; control group 52 cases, 13 males and 39 females, age 37a ± 11a. Headache attack, the patient randomized alternately oral containing lysine aspirin 0.9g plus metoclopramide 10mg capsules (treatment group) or capsule containing starch (control group) a. Results: The total effective rate of 4h in treatment group was 88%; the total effective rate in control group was 29%. There was significant difference between the two groups in the total effective rate (P <0. 01), no serious adverse reactions. CONCLUSION: Migraine and metoclopramide are safe and reliable.