测定灭鼠药急性经口毒性,常用灌粉或灌胃法。由于灭鼠药力强,应投的纯药量少,为减少给药时的相对损耗,增加试验剂量的准确性,需将药品先行稀释。以往介绍药品应稀释浓度的运算过程如下: 1、应给纯药量(毫克或微升)=试验剂量(毫克/克公斤或微升/公斤)×鼠体重(公斤)……[1] Determination of anti-rat poisoning acute oral toxicity, commonly used powder or gavage method. Due to the strong anti-rodent drug should be cast less pure drug, in order to reduce the relative loss when administered, increasing the accuracy of the test dose, the drug need to be first diluted. In the past, the procedure for calculating the concentration of a drug to be diluted should be as follows: 1. The amount of pure drug (mg or microliters) = the test dose (mg / g kg or microliters / kg) × rat body weight (kg)