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从贫血病人尿中提取红细胞生成素(Erythropoietin)简称EPO制剂(7A)及其生物活性分析已获成功。 本制剂在饥饿大鼠上用~(59)Fe掺入红细胞和网织红细胞为反应指标,定其活性单位。结果经统计分析确定其活性为10u/mg蛋白质。并能明显增加骨髓中红系造血细胞数量。
The extraction of erythropoietin (EPO) (1A) from the urine of anemic patients and its bioactivity analysis have been successful. The preparation of starvation rats with ~ (59) Fe incorporation of red blood cells and reticulocytes as reaction indicators, set the activity unit. Results The activity was determined as 10 u / mg protein by statistical analysis. And can significantly increase the number of erythroid hematopoietic cells in the bone marrow.