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目的探讨绝经和非绝经妇女宫颈细胞学刮片检查在宫颈癌疾病检出率的对比效果。方法选择武宣县妇幼保健院2013年1月至2014年6月接受宫颈疾病筛查的2513例绝经妇女和2515例非绝经妇女作为研究对象,对所有纳入研究的受试者行宫颈细胞学刮片检查及宫颈人乳头瘤病毒(HPV)检查,对比绝经和非绝经妇女的筛查结果,判断两组研究对象宫颈癌的检出率及HPV感染率,并对诊断为宫颈癌以外的研究对象进行12个月的随访。结果绝经和非绝经妇女宫颈癌的检出率分别为0.159%和0.239%,两组比较差异未见统计学意义(P>0.05);HPV感染率分别为20.9%和21.5%,两组比较差异未见统计学意义(P>0.05);对宫颈癌以外的研究对象随访检查结果示,绝经和非绝经妇女宫颈相关疾病的检出率比较差异有统计学意义(P<0.05)。结论绝经和非绝经妇女宫颈癌的发病率及HPV感染率未见明显差异,但是通过随访发现绝经妇女的宫颈相关疾病的发病率高于非绝经妇女,绝经后妇女更容易发展为高级别的病变,应当引起临床的高度重视。
Objective To investigate the contrast effect of cervical cytology smears in detecting cervical cancer in menopausal and non-menopausal women. Methods Wuxuan County Maternal and Child Health Hospital from January 2013 to June 2014 cervical screening screening of 2513 cases of postmenopausal women and 2515 cases of non-menopausal women as the research object, all the subjects included in the study cervical cytology scraps Examinations and cervical HPV test to compare the screening results of women in both menopause and non-menopausal women to determine the detection rate of cervical cancer and HPV infection rate in two groups of subjects and to study the subjects other than cervical cancer 12 months follow-up. Results The detection rates of cervical cancer in menopausal and non-menopausal women were 0.159% and 0.239% respectively, with no significant difference between the two groups (P> 0.05). The HPV infection rates were 20.9% and 21.5% No statistically significant (P> 0.05). The follow-up examination of subjects other than cervical cancer showed that the detection rate of cervical-related diseases in menopausal and non-menopausal women was significantly different (P <0.05). Conclusions There is no significant difference in the incidence of cervical cancer and HPV infection among menopausal and non-menopausal women. However, the incidence of cervical-related diseases in postmenopausal women is higher than that in non-menopausal women, and postmenopausal women are more likely to develop high-grade lesions , Should cause clinical attention.