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肾脏纤维化是所有慢性肾脏疾病进展至终末期肾衰的共同通路 ,其本质是细胞外基质 (ｅｘｔｒａｃｅｌｌｕｌａｒｍａｔｒｉｘ ,ＥＣＭ)在肾小球和肾间质异常堆积 ,导致肾毁损和肾功能进行性下降。ＥＣＭ的过多堆积缘于ＥＣＭ的产生增多和 /或降解减少。近年来 ,关于ＥＣＭ解降系
Renal fibrosis is the common pathway of progression from all chronic renal diseases to end-stage renal failure. The essence is that extracellular matrix (ECM) accumulates abnormally in glomerulus and renal interstitium, leading to renal damage and the progressive decline of renal function. Excess accumulation of ECMs is due to increased ECM production and / or reduced degradation. In recent years, on the ECM solution system